175 Maternal Diet and Type 2 Diabetes in the Offspring

Maternal Diet, Behaviour and Offspring Skeletal Health

Osteoporotic fracture has a major impact upon health, both in terms of acute and long term disability and economic cost. Peak bone mass, achieved in early adulthood, is a major determinant of osteoporosis risk in later life. Poor early growth predicts reduced bone mass, and so risk of fracture in later life. Maternal lifestyle, body build and 25(OH) vitamin D status predict offspring bone mass....

The Interaction between Diet and Air Pollution in Association with Type 2 Diabetes Mellitus: Introducing Yazd Health Study

A maternal gluten-free diet reduces inflammation and diabetes incidence in the offspring of NOD mice.

Early-life interventions in the intestinal environment have previously been shown to influence diabetes incidence. We therefore hypothesized that a gluten-free (GF) diet, known to decrease the incidence of type 1 diabetes, would protect against the development of diabetes when fed only during the pregnancy and lactation period. Pregnant nonobese diabetic (NOD) mice were fed a GF or standard die...

Perception of offspring risk for type 2 diabetes among patients with type 2 diabetes and their adult offspring.

R elatives of type 2 diabetic patients are at higher risk for type 2 diabetes, as they are likely to share genetic predisposition and have similar lifestyle habits (1). To actively involve high-risk individuals in prevention, recognition of disease risk is crucial (2). Some studies have suggested that Japanese are genetically predisposed to diabetes (3,4), so recognition of risk by highrisk Jap...

Protective effects of troxerutin on maternal high-fat diet-induced impairments of spatial memory and apelin in the male offspring

Objective(s): Maternal high-fat diet (HFD) is linked with metabolic and cognitive deficits in offspring. Neuroprotective effects of troxerutin, a natural bioflavonoid, have been reported recently. This study aimed to investigate the effects of troxerutin on spatial memory and serum and hippocampal apelin levels in the male offspring of HFD fed mothers.Materials and Methods: Three-week-old femal...